Systematic reviews and meta-analyses by Brazilian scientists
Effect of maternal dysbiosis on offspring behavioral outcomes, a systematic review, and meta-analysis.
Protocol pre-registered on the PROSPERO platform describing the methodology used for the systematic review and meta-analysis of studies investigating the effects of maternal dysbiosis on the behavior of offspring in experimental animals.
Authors: Frederico Ferreira, Lucas Hassib, Guilherme Rouvier, Alexandre Kanashiro, Alline Campos
Citation: Frederico Ferreira, Lucas Hassib, Guilherme Rouvier, Alexandre Kanashiro, Alline Campos. Effect of maternal dysbiosis on offspring behavioral outcomes, a systematic review, and meta-analysis. PROSPERO 2022 CRD42022289224. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022289224 . Accessed in Jun 21, 2025.
Contact: Frederico Ferreira - frederico dot ferreira at ioc dot fiocruz dot br
Systematic Review and Network Meta-analysis: Efficacy of 21 antidepressants in predictive tests of antidepressant action in stressed rodents
Protocol pre-registered on the PROSPERO platform describing the methodology employed for the systematic review and network meta-analysis of studies investigating the antidepressant activity of 21 antidepressant compounds in predictive tests of activity in stressed laboratory rodents
Authors: Tamires Martins, Georgine Accrombessi, Maël Lemoine, Etienne Billette de Villemeur, Catherine Belzung, Cilene Lino de Oliveira
Citation: Tamires Martins, Georgine Accrombessi, Maël Lemoine, Etienne Billette de Villemeur, Catherine Belzung, Cilene Lino de Oliveira. Systematic Review and Network Meta-analysis: Efficacy of 21 antidepressants in predictive tests of antidepressant action in stressed rodents. PROSPERO 2021 CRD42021221778. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021221778. Accessed in Jun 21, 2025.
Contact: Tamires Martins - camaradesbr at gmail dot com
Medial prefrontal cortex controlling the immobility of rats in the forced swimmings test: a systematic review and meta-analysis
Results of a systematic review and meta-analysis published in a preprint platform on the role of the prefrontal cortex in controlling the immobility of laboratory rats during the forced swim test
Authors: Karolina Domingues, Fernando F Melleu, Cilene Lino de Oliveira
Citation: Medial prefrontal cortex controlling the immobility of rats in the forced swimmings test: a systematic review and meta-analysis. K Domingues, FF Melleu, CL de Oliveira - bioRxiv, 2021. Available at https://www.biorxiv.org/content/10.1101/2021.04.27.441685v1.abstract . Accessed in Jun 21, 2025.
Contact: Karolina Domingues - dominguesk dot karolina at gmail dot com
A compact guide to the systematic review and meta-analysis of the literature in neuroscience
A compact guide on how to design a review question, plan, implement a protocol, and publish the results of a systematic review and meta-analysis in the field of Neuroscience
Authors: Juliana A Bolzan, Cilene Lino de Oliveira
Citation: Bolzan, J. A., & Lino de Oliveira, C. (2022). A compact guide to the systematic review and meta-analysis of the literature in neuroscience. Journal for Reproducibility in Neuroscience, 2. https://doi.org/10.31885/jrn.2.2021.1669. Available at https://journals.helsinki.fi/jrn/article/view/1669. Accessed in Jun 21, 2025.
Contact: Cilene Lino de Oliveira - cilene dot lino at ufsc dot com
How does publication bias skew the effect size estimate of antidepressants in the forced swim test?
Protocol published in a peer-reviewed journal describing the methodology used for systematic review and meta-analysis of studies investigating the effects of prototypical antidepressants on laboratory rodent immobility in the forced swim test.
Authors: Ana Ramos-Hryb, Cari Harris, Omorose Aighewi, Cilene Lino de Oliveira
Citation: Ramos-Hryb AB, Harris C, Aighewi O, Lino-de-Oliveira C. How would publication bias distort the estimated effect size of prototypic antidepressants in the forced swim test? Neurosci Biobehav Rev. 2018 Sep;92:192-194. doi: 10.1016/j.neubiorev.2018.05.025. Epub 2018 Jun 7. PMID: 29886179. Available at https://camaradesbrasil.bio.br/. Accessed in Jun 21, 2025.
Contact: Cilene Lino de Oliveira - cilene dot lino at ufsc dot br
Protocol for a systematic review and meta-analysis of data from preclinical studies employing forced swimming test: an update
First protocol update for publication in a peer-reviewed journal by peers describing the methodology used for systematic review and meta-analysis of studies investigating the effects of prototypical antidepressants on immobility of laboratory rodents in the forced swim test
Authors: Ana Ramos-Hryb, Zsanett Bahor, Sarah McCann, Emily Sena, Malcom MacLeod, Cilene Lino de Oliveira
Citation: Ramos-Hryb AB, Bahor Z, McCann S, et al Protocol for a systematic review and meta-analysis of data from preclinical studies employing forced swimming test: an update. BMJ Open Science 2019;3:e000043. . Available at https://dx.doi.org/10.1136/bmjos-2017-000043. Accessed in Jun 21, 2025.
Contact: Cilene Lino de Oliveira - cilene dot lino at ufsc dot br
An updated protocol for the systematic review and meta-analysis of data from animal studies employing the forced swimming test
Second protocol update for pre-registration on the PROSPERO platform. Document describes the methodology used for systematic review and meta-analysis of studies investigating the effects of prototypical antidepressants on laboratory rodent immobility in the forced swimming test.
Authors: Tamires Martins, Ana Belén Ramos Hryb, Marcus Antonio Policarpo, Cilene Lino de Oliveira
Citation: Tamires Martins, Ana Belén Ramos Hryb, Marcus Antonio Policarpo, Cilene Lino de Oliveira. An updated protocol for the systematic review and meta-analysis of data from animal studies employing the forced swimming test. PROSPERO 2020 CRD42020200604. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020200604. Accessed in Jun 21, 2025.
Contact: Tamires Martins - camaradesbr at gmail dot com
Blood Pressure Effects In Male And Female Rats Due To Antidepressant Use: A Systematic Review And Meta-Analysis.
Protocol pre-registered on the PROSPERO platform describing the methodology used for the systematic review and meta-analysis of studies investigating the effects of antidepressants on blood pressure in laboratory rats.
Authors: Thayná Marinho dos Santos, Aurea Elizabeth Linder, Sara Raquel de Oliveira Gomes.
Citation: Thayná Marinho dos Santos, Aurea Elizabeth Linder, Sara Raquel de Oliveira Gomes. Blood Pressure Effects In Male And Female Rats Due To Antidepressant Use: A Systematic Review And Meta-Analysis. PROSPERO 2021 CRD42021277987. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021277987. Accessed in Jun 21, 2025.
Contact: Thayná Marinho dos Santos - thaynamarinho22 at gmail dot com
Can anti-inflammatory agents improve L-DOPA-induced dyskinesia in parkinsonian animals?
Protocol pre-registered on the PROSPERO platform describing the methodology used for the systematic review and meta-analysis of studies investigating the effects of anti-inflammatory drugs on L-DOPA-induced dyskinesia in parkinsonian laboratory animals.
Authors: Cilene Lino de Oliveira, Daniel Mendes Filho, Leonardo Calaça Arruda Vanderlei, Elaine Del Bel
Citation: Cilene Lino de Oliveira, Daniel Mendes Filho, Leonardo Calaça Arruda Vanderlei, Elaine Del Bel. Can anti-inflammatory agents improve L-DOPA-induced dyskinesia in parkinsonian animals?. PROSPERO 2020 CRD42020203826. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020203826 . Accessed in Jun 21, 2025.
Contact: Prof Dr Elaine Del Bel - eadelbel at forp dot usp dot br
Antidepressant-like effects of Cannabidiol: A Systematic Review and Meta-Analysis of animal studies
Protocol published in a peer-reviewed journal describing the methodology used for systematic review and meta-analysis of studies investigating the effects of prototypical antidepressants on laboratory rodent immobility in the forced swim test.
Authors: Ariandra Sartim, Vanessa Beijamini, Samia Joca, Cilene de Oliveira, Roberto Andreatini, Kennia Silveira.
Citation: Ariandra Sartim, Vanessa Beijamini, Samia Joca, Cilene de Oliveira, Roberto Andreatini, Kennia Silveira. Antidepressant-like effects of Cannabidiol: A Systematic Review and Meta-Analysis of animal studies. PROSPERO 2020 CRD42020210067. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020210067. Accessed in Jun 21, 2025.
Contact: Ariandra Sartim - ariandrag at hotmail dot com
Antidepressant treatment and behavior responses in Drosophila melanogaster: a systematic review and metanalysis
Protocol pre-registered on the PROSPERO platform describing the methodology used for the systematic review and meta-analysis of studies investigating the effects of prototypical antidepressants on laboratory fruit flies observed in behavioral tests
Authors: Fabiola Eckert, Fabiani Triches, Johnny Costa, Cilene Lino de Oliveira
Citation: Fabiola Eckert, Fabiani Triches, Johnny Costa, Cilene Lino de Oliveira. Antidepressant treatment and behavior responses in Drosophila melanogaster: a systematic review and metanalysis. PROSPERO 2020 CRD42020225423. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020225423. Accessed in Jun 21, 2025.
Contact: Fabiola Eckert - fabieckert at gmail dot com
Alterations of parvalbumin-positive interneurons in animal models of schizophrenia: a systematic and meta-analysis
Protocol pre-registered on the PROSPERO platform describing the methodology used for the systematic review and meta-analysis of studies investigating the number of parvalbumin-positive neurons in the brain of laboratory animals with a schizophrenia-like phenotype
Authors: Debora Fabris, Thamyris Silva, Francisco Guimarães, Felipe Gomes
Citation: Debora Fabris, Thamyris Silva, Francisco Guimarães, Felipe Gomes. Alterations of parvalbumin-positive interneurons in animal models of schizophrenia: a systematic and meta-analysis review. PROSPERO 2020 CRD42020214421. Available at https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020214421. Accessed in Jun 21, 2025.
Contact: Francisco Guimarães - fsguimar at fmrp dot usp dot br
Protocol for systematic review and meta-analysis of the evidence linking hippocampal neurogenesis to the effects of antidepressants on mood and behaviour
Protocol published in a peer-reviewed journal describing the methodology employed for the systematic review and meta-analysis of studies investigating the relationship between hippocampal neurogenesis and antidepressant activity in laboratory rodents
Authors: Juliana A Bolzan, Cilene Lino de Oliveira
Citation: Bolzan JA, Lino de Oliveira C. Protocol for systematic review and meta-analysis of the evidence linking hippocampal neurogenesis to the effects of antidepressants on mood and behaviour. BMJ Open Science 2021;5:e100077. doi: 10.1136/bmjos-2020-100077. Available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647582/. Accessed in Jun 21, 2025.
Contact: Juliana Bolzan - camaradesbr at gmail dot com
Do antidepressants promote neurogenesis in adult hippocampus? A systematic review and meta-analysis on naive rodents
Results of a systematic review and meta-analysis published in a peer-reviewed journal on the effects of antidepressant treatment on hippocampal neurogenesis in unstressed laboratory rodents
Authors: Juliana A Bolzan, Cilene Lino de Oliveira
Citation: Cilene Lino de Oliveira, Juliana Aparecida Bolzan, Alexandre Surget, Catherine Belzung, Do antidepressants promote neurogenesis in adult hippocampus? A systematic review and meta-analysis on naive rodents. Pharmacology & Therapeutics, 210, 2020, 107515, ISSN 0163-7258, https://doi.org/10.1016/j.pharmthera.2020.107515.. Available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8647582/. Accessed in Jun 21, 2025.
Contact: Cilene Lino de Oliveira - cilene dot lino at ufsc dot com
